How Does Meth Work?
Since meth belongs to the amphetamine family of drugs, it works much in the same way as many other amphetamines/stimulants. Since meth induces the release and inhibits the reuptake of the neurotransmitters dopamine and norepinephrine, it sends pleasure impulses to the brain which results in the creation of strong but artificial pleasure sensations.
Compared to other amphetamines, methamphetamine can produce the strongest dopamine increase and the most powerful stimulation, for the longest duration. The effects can last over 48 hours, making it one of the most effective “highs” and most addictive drugs available on the streets.
With such a huge change in neurotransmitters, the brain quickly becomes accustomed to the effect and dependent on the drug. Since this can happen within the first or second time using, it’s obvious that the drug would be so highly addictive and dangerous.